Natural, artificial and dynamic fractures are always induced by water injection in the peripheral low?permeability fractured reservoirs of Daqing. The water breakthrough types of production wells are different due to the complex fracture system, and the water breakthrough rules and causes are complex as well, which increase the difficulty of measure adjustment. In order to improve the water flooding effect of low permeability fractured reservoir, the water breakthrough types of single well, taking C45Z block in the CYG oilfield as the research object, were divided based on the fracture formation characteristics of the block reservoir. The water breakthrough rules and forming causes were systematically analyzed from dynamic and static data, so as to point out the resolution strategy for the adjustment of measures. Using the optimized methods, the average daily oil production of the sample well group increased by 1.0 t, the water cut was reduced by 12.0%, and the cumulative oil production increase in each stage was 2 051.6 t until March 2021. In this way, the adjustment mode of classified treatment measures initially formed.